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Among its related pathways are Metabolism and Alzheimers disease

The active form of the protein is found extracellularly as a disulfide-linked homodimer

p53 Polyclonal Antibody, 20ul[BT-AP06815] 3D Cell Culture Consumables Conquer the challenges of cellTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.