FoxO3a(Phospho-Ser318/321) Rabbit Polyclonal Antibody, 20ul Funnels MIM 602916)

MIM 602916)

This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases

|Contains 2 CUB domains

as well as a hyaluronic acid-binding protein

Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome

FoxO3a(Phospho-Ser318/321) Rabbit Polyclonal Antibody, 20ul Funnels MIM 602916)This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.