UBE2D2 Polyclonal Antibody, 100ul Deep Well Plates The encoded protein is involved

The encoded protein is involved in many cellular processes

Modulates the placental expression of CYP11A1

Defects in CYB5A are a cause of type IV hereditary methemoglobinemia

This gene is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers

This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF| and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II)| making it available for initiation of gene expression

UBE2D2 Polyclonal Antibody, 100ul Deep Well Plates The encoded protein is involvedRegulated degradation of misfolded, damaged or short lived proteins in eukaryotes occurs via the ubiquitin (Ub) proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub containing proteins to form polymeric chains, marking them as targets for 26S proteasome mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating),