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SNX4 Polyclonal Antibody, 50ul Long RNA Synthesis ISGF3 binds to the IFN

SKU: 47426873307

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SNX4 Polyclonal Antibody, 50ul Long RNA Synthesis ISGF3 binds to the IFNSNX4 (sorting nexin 4) encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may

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Description

ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes| which drive the cell in an antiviral state

GBP5 (Guanylate Binding Protein 5) is a Protein Coding gene

When activated| the encoded protein is known to inhibit CDC25C phosphatase| preventing entry into mitosis| and has been shown to stabilize the tumor suppressor protein p53| leading to cell cycle arrest in G1

|The C1 domain| containing the phorbol ester/DAG-type region 1 (C1A) and 2 (C1B)| is the diacylglycerol sensor and the C2 domain is a non-calcium binding domain

Translocation t(1

SNX4 Polyclonal Antibody, 50ul Long RNA Synthesis ISGF3 binds to the IFNSNX4 (sorting nexin 4) encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may

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