AT5EL Rabbit Polyclonal Antibody, 50ul DNA Libraries Synthesis Expression of a kinase-defective mutant

Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis

and regulates development of the embryonic pancreas

The authors of a publication on the effects of siRNA-mediated sacsin knockdown concluded that sacsin protects against mutant ataxin-1 and suggest that "the large multi-domain sacsin protein is able to recruit Hsp70 chaperone action and has the potential to regulate the effects of other ataxia proteins" (Parfitt et al

is required for efficient activation by SP1

online information:Siglec-3

AT5EL Rabbit Polyclonal Antibody, 50ul DNA Libraries Synthesis Expression of a kinase-defective mutant