IBTK Polyclonal Antibody, 20ul Modification Enzymes The protein localizes to the
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IBTK Polyclonal Antibody, 20ul Modification Enzymes The protein localizes to theBruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK mediated calcium mobilization and negatively regulates the activation of nuclear factor kappa B driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple
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