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SPE39 Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance with symptoms including severe mononucleosis

SKU: 4948842992

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SPE39 Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance with symptoms including severe mononucleosisThis gene encodes a protein involved in the sorting of lysosomal proteins. Mutations in this gene are associated with ARCS2 (arthrogryposis renal dysfunction and cholestasis 2). Alternative splicing results in multiple transcript variants.

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Description

with symptoms including severe mononucleosis and malignant lymphoma

The promoter of this gene is frequently hypermethylated in these cancer tissues| although the hypermethylation does not appear to be the cause of the reduced expression of this gene

There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2

The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates

which may contribute to its ability to reduce the tumorigenic phenotype in cells

SPE39 Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance with symptoms including severe mononucleosisThis gene encodes a protein involved in the sorting of lysosomal proteins. Mutations in this gene are associated with ARCS2 (arthrogryposis renal dysfunction and cholestasis 2). Alternative splicing results in multiple transcript variants.

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