Histone H4 (Di Methyl Lys59) Polyclonal Antibody, 100ul Yeast Expression Mutations in this gene may

Mutations in this gene may be associated with hereditary nonpolyposis colon cancer

the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF

and may play an important role in nervous system development

that is closely related to both the placental and intestinal forms of alkaline phosphatase

The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface

Histone H4 (Di Methyl Lys59) Polyclonal Antibody, 100ul Yeast Expression Mutations in this gene mayHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.