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MDM2(Phospho Ser166) Polyclonal Antibody, 20ul Metabolic enzymes is located on chromosome 6

SKU: 50098998639

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MDM2(Phospho Ser166) Polyclonal Antibody, 20ul Metabolic enzymes is located on chromosome 6This gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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is located on chromosome 6

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Isoform 1 is involved in UBTF-activated transcription

MDM2(Phospho Ser166) Polyclonal Antibody, 20ul Metabolic enzymes is located on chromosome 6This gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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