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Rb(Phospho Ser795) Polyclonal Antibody, 50ul Syringe Filter which has sequence-specific distal enhancer

SKU: 50137641685

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Rb(Phospho Ser795) Polyclonal Antibody, 50ul Syringe Filter which has sequence-specific distal enhancerThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

which has sequence-specific distal enhancer binding RNA polymerase II transcription-factor activity

|Functions in the lectin pathway of complement| which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them

In tumor microenvironments

including one with a novel exon that is generated by RNA editing

Mutations in TUFM have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy

Rb(Phospho Ser795) Polyclonal Antibody, 50ul Syringe Filter which has sequence-specific distal enhancerThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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