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CUL-1 Polyclonal Antibody, 50ul[BT-AP08191] Filtration The enzyme is important in
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CUL-1 Polyclonal Antibody, 50ul[BT-AP08191] Filtration The enzyme is important inCore component of multiple cullin RING based SCF (SKP1 CUL1 F box protein) E3 ubiquitin protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1 F box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin conjugating enzyme. The E3
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