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Synuclein- Alpha Polyclonal Antibody, 50ul[BT-AP08723] Oligo Pool a large family of proteins

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Synuclein- Alpha Polyclonal Antibody, 50ul[BT-AP08723] Oligo Pool a large family of proteinsAlpha synuclein is a member of the synuclein family, which also includes beta and gamma synuclein. Synucleins are abundantly expressed in the brain and alpha and beta synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with

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Description

a large family of proteins that regulate axon guidance

Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined

Mutations in GNAL have been associated with dystonia 25 and this gene is located in a susceptibility region for bipolar disorder and schizophrenia

Polymorphisms of this gene may be associated with hunger

Directly involved in heterochromatin formation by maintaining overall chromatin structure and| in particular| that of constitutive heterochromatin by stabilizing histone methylation

Synuclein- Alpha Polyclonal Antibody, 50ul[BT-AP08723] Oligo Pool a large family of proteinsAlpha synuclein is a member of the synuclein family, which also includes beta and gamma synuclein. Synucleins are abundantly expressed in the brain and alpha and beta synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with

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