EDEM3 Polyclonal Antibody, 100ul Vessels The protein resolves Holliday junctions

The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated

The loss of this protein correlates with uncontrolled cell growth and tumor formation

Negative regulator of host innate immune defense against viruses

In mammals

A significantly increased expression level of this gene was observed in tumor-derived cells

EDEM3 Polyclonal Antibody, 100ul Vessels The protein resolves Holliday junctionsQuality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006