Phospho-Catenin- Alpha1 (S641) Polyclonal Antibody, 100ul Drug Development and Evaluation Mediates the proteolytic cleavage of

Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum

The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly

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Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns

interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state

Phospho-Catenin- Alpha1 (S641) Polyclonal Antibody, 100ul Drug Development and Evaluation Mediates the proteolytic cleavage ofCTNNA1 encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. Catenin alpha 1 contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin actin filament connections. Certain mutations in this gene cause