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FEN-1 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation This protein preferentially induces apoptosis

SKU: 50991592641

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FEN-1 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation This protein preferentially induces apoptosisFlap endonuclease 1 encoded by FEN1 removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG RAD2 endonuclease family and is

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Description

This protein preferentially induces apoptosis in transformed and tumor cells

The protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains

The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins

This encoded protein may play a role in protein kinase C signaling

Adapter protein that links FGR and NGF receptors to downstream signaling pathways

FEN-1 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation This protein preferentially induces apoptosisFlap endonuclease 1 encoded by FEN1 removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG RAD2 endonuclease family and is

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