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EP-CAM Polyclonal Antibody, 100ul[BT-AP02987] Liquid Storage Consumables This gene also has pseudogenes

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EP-CAM Polyclonal Antibody, 100ul[BT-AP02987] Liquid Storage Consumables This gene also has pseudogenesEPCAM encodes a carcinoma associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in EPCAM result in congenital tufting enteropathy.

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Description

This gene also has pseudogenes on chromosomes 9

Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms

This gene encodes a protein that is highly similar to the yeast SIN1 protein| a stress-activated protein kinase

This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases

this gene was found to be required for the correct formation of the optic fissure and other aspects of retinal development

EP-CAM Polyclonal Antibody, 100ul[BT-AP02987] Liquid Storage Consumables This gene also has pseudogenesEPCAM encodes a carcinoma associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in EPCAM result in congenital tufting enteropathy.

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