OATP1 Polyclonal Antibody, 50ul Protein Expression Ligand binding activates the receptor

Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation

generated by use of alternative translational start codons

This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1

Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia

MIM 179550)

OATP1 Polyclonal Antibody, 50ul Protein Expression Ligand binding activates the receptorSLCO1A2 encodes a sodium independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of SLCO1A2 results in multiple transcript variants.