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RAD9(Phospho Ser272) Rabbit Polyclonal Antibody, 50ul DNA Oligo Synthesis Mutations in this gene result

SKU: 51790693

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RAD9(Phospho Ser272) Rabbit Polyclonal Antibody, 50ul DNA Oligo Synthesis Mutations in this gene resultCatalytic activity: Exonucleolytic cleavage in the 3' to 5' direction to yield nucleoside 5' phosphates. Component of the 9 1 1 cell cycle checkpoint response complex that plays a major role in DNA repair. The 9 1 1 complex is recruited to DNA lesion upon damage by the RAD17 replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long patch base excision repair (LP BER). The 9 1 1

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Description

Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia

Prevents the cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains

where it phosphorylates and inactivates BCKD

This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division

Beta subunits are composed of five domains

RAD9(Phospho Ser272) Rabbit Polyclonal Antibody, 50ul DNA Oligo Synthesis Mutations in this gene resultCatalytic activity: Exonucleolytic cleavage in the 3' to 5' direction to yield nucleoside 5' phosphates. Component of the 9 1 1 cell cycle checkpoint response complex that plays a major role in DNA repair. The 9 1 1 complex is recruited to DNA lesion upon damage by the RAD17 replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long patch base excision repair (LP BER). The 9 1 1

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