IRF-3 Polyclonal Antibody, 50ul[BT-AP10493] Enzyme Activity Assays Belongs to the PRPF40 family

Belongs to the PRPF40 family

a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex

and thus it participates in the death signaling initiated by these receptors

including cell polarization and migration

and it is thought to mediate estrogen actions in breast cancer as a primary response gene

IRF-3 Polyclonal Antibody, 50ul[BT-AP10493] Enzyme Activity Assays Belongs to the PRPF40 familyThis gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been