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SEN2 Polyclonal Antibody, 50ul Buffers & Solutions covalent attachment of UBLs does

SKU: 5200598992

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SEN2 Polyclonal Antibody, 50ul Buffers & Solutions covalent attachment of UBLs doesThis gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

covalent attachment of UBLs does not result in degradation of the modified proteins

Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia

There are three isoforms of ATG16L2 and the molecular weight of three isoform is respectively 69kDa

some seem to shuttle between the nucleus and the cytoplasm

colon and intestine

SEN2 Polyclonal Antibody, 50ul Buffers & Solutions covalent attachment of UBLs doesThis gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.

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