c-Abl(Phospho-Tyr89) Rabbit Polyclonal Antibody, 100ul Enzyme-Linked Immunosorbent Assay (ELISA) including nonhuman primates

including nonhuman primates

The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors

Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene

Associated with EGFR

family crosslink spectrin and interact with other cytoskeletal proteins

c-Abl(Phospho-Tyr89) Rabbit Polyclonal Antibody, 100ul Enzyme-Linked Immunosorbent Assay (ELISA) including nonhuman primatesThis gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes including cell division adhesion differentiation and response to stress. The activity of the protein is negatively regulated by its SH3 domain whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation suggesting a