SLUG Monoclonal Antibody, 100ul Mammalian Expression It recruits the N-CoR repressor

It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters

The proteins encoded by these genes form disulfide bonds with cysteine residues in hair keratins| thereby contributing to the structure and stability of hair fibers

The authors of a publication on the effects of siRNA-mediated sacsin knockdown concluded that sacsin protects against mutant ataxin-1 and suggest that "the large multi-domain sacsin protein is able to recruit Hsp70 chaperone action and has the potential to regulate the effects of other ataxia proteins" (Parfitt et al

and it contributes to spinal sensitization and neuropathic pain states

The expression of MYL7 in heart is predominatantly restricted to the atrium

SLUG Monoclonal Antibody, 100ul Mammalian Expression It recruits the N-CoR repressorThis gene encodes a member of the Snail family of C2H2 type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E box motifs and is also likely to repress E cadherin transcription in breast carcinoma. This protein is involved in epithelial mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.