GAS3 Polyclonal Antibody, 50ul Insect Expression HIST1H2AI is found in the

HIST1H2AI is found in the small histone gene cluster on chromosome 6p22-p21

It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines

The SFPQ-NONO heteromer may be involved in DNA unwinding by modulating the function of topoisomerase I/TOP1

It binds cytidine-rich sequences in double-stranded DNA

Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization| inositol triphosphate production and secretion of IL6 and CSF1

GAS3 Polyclonal Antibody, 50ul Insect Expression HIST1H2AI is found in thePMP22 (peripheral myelin protein 22) encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue specific expression. Various mutations of PMP22 are causes of Charcot Marie Tooth disease Type IA, Dejerine Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants.