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ATP-citrate synthase Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Made from durable PS material

SKU: 52201272674

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ATP-citrate synthase Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Made from durable PS materialATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl CoA, serves several important biosynthetic pathways, including lipogenesis

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Description

Made from durable PS material

Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients

the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs

Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported

Is also detected in several tumors types

ATP-citrate synthase Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Made from durable PS materialATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl CoA, serves several important biosynthetic pathways, including lipogenesis

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