PDK1(Phospho Ser241) Polyclonal Antibody, 50ul Nucleic Acid Amplification This PTP contains two tandem

This PTP contains two tandem Src homology-2 domains| which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates

The protein encoded by IGFALS is a serum protein that binds insulin-like growth factors

heart and kidney

a cytoplasmic form and a mitochondrial form

and breast cancer

PDK1(Phospho Ser241) Polyclonal Antibody, 50ul Nucleic Acid Amplification This PTP contains two tandemCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,Phosphorylates and activates not only PKB AKT, but also PKA, PKC zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.,PTM: Phosphorylated on tyrosine and serine threonine. Phosphorylation on Ser 241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser 241,