PDCD5 Polyclonal Antibody, 50ul Purification The protein has been localized

The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction

Belongs to the AP-2 family

Alterations in the encoded protein may be associated with susceptibility to autism spectrum disorder

essential for cell survival and development

Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK-homology regions

PDCD5 Polyclonal Antibody, 50ul Purification The protein has been localizedThis gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12