CD58 Polyclonal Antibody, 50ul[BT-AP02250] Cell Function Analysis Loeys-Deitz Aortic Aneurysm Syndrome

Loeys-Deitz Aortic Aneurysm Syndrome

The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A

Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6)

It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally

placenta and stomach as well as in colon tumor

CD58 Polyclonal Antibody, 50ul[BT-AP02250] Cell Function Analysis Loeys-Deitz Aortic Aneurysm SyndromeThe activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by MED14 (mediator complex subunit 14) is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1.