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NEIL3 Polyclonal Antibody, 50ul Culture Media mutations in either gene may

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NEIL3 Polyclonal Antibody, 50ul Culture Media mutations in either gene mayNEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.

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Description

mutations in either gene may contribute to these disorders

This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12

This protein is associated with the nuclear matrix in perichromatin fibrils and

Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds

An important paralog of this gene is MAP4K3

NEIL3 Polyclonal Antibody, 50ul Culture Media mutations in either gene mayNEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.

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