RANB3 Rabbit Polyclonal Antibody, 50ul Shakers Breast cancer metastasis-suppressor 1 encoded

Breast cancer metastasis-suppressor 1 encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC)

All variants share the N-terminal region in common

including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion

This gene is clustered with family members FADS1 and FADS2 at 11q12-q13

The human genome contains five pseudogenes related to this gene| at least one of which is transcribed

RANB3 Rabbit Polyclonal Antibody, 50ul Shakers Breast cancer metastasis-suppressor 1 encodedThis gene encodes a protein with a RanBD1 domain that is found in both the nucleus and cytoplasm. This protein plays a role in nuclear export as part of a heteromeric complex. Alternate transcriptional splice variants encoding different isoforms have been characterized.