JAML1 Polyclonal Antibody, 20ul Immune Cell Preparation Has a key role in

Has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons

also known as BCSC-1 (breast cancer suppressor candidate 1) or LOH11CR2A (loss of heterozygosity 11 chromosomal region 2 gene A protein)

The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus

Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene

This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis

JAML1 Polyclonal Antibody, 20ul Immune Cell Preparation Has a key role inThe Ig like V type domain 2 mediates interaction with CXADR.,May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells.,induction: Up regulated upon retinoic acid, Me2SO and PMA treatment in