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Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly

Freeman-Sheldon syndrome and Sheldon-Hall syndrome

It possesses histone deacetylase activity and represses transcription when tethered to a promoter

Upregulated expression of this gene in astroglial cells upon exposure to lipopolysaccharides suggests a function for the encoded protein in the brain

HNF6 Polyclonal Antibody, 50ul Sealing Film take the easy road toThis gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver expressed genes, and antagonizes glucocorticoid stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple