ASPP2 Polyclonal Antibody, 50ul Cryopreservation This subunit has been shown

This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells

This PTP can interact with scaffolding protein RACK1/GNB2L1

and may play an important role in nervous system development

and is overexpressed in the brain of Down syndrome fetuses

via the formation of a high-energy thioester bond

ASPP2 Polyclonal Antibody, 50ul Cryopreservation This subunit has been shownThis gene encodes a member of the ASPP (apoptosis stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different