dTMP Kinase Polyclonal Antibody, 50ul Low-speed Centrifuges MSH6 encodes a member of

MSH6 encodes a member of the DNA mismatch repair MutS family

glycosylated alpha subunit and two smaller beta subunits

This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB)| both anchored in the membrane

It may function as an integrator of transcription repression and nuclear receptor signaling

Alternatively spliced transcript variants encoding different isoforms have also been described for this gene

dTMP Kinase Polyclonal Antibody, 50ul Low-speed Centrifuges MSH6 encodes a member ofThymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5 Fluorouracil (5 FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle