CRLF1 Polyclonal Antibody, 50ul Pathway and Network Analysis Mutations in the promoter region

Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers

some protein-coding and others not protein-coding

SSF1 is known to be involved in the second step of mRNA splicing

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Interacts with AKAP9

CRLF1 Polyclonal Antibody, 50ul Pathway and Network Analysis Mutations in the promoter regionThis gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold induced sweating syndrome.