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Axl Polyclonal Antibody, 100ul[BT-AP00783] Dry Bath Additionally| this gene supports metastatic

SKU: 55174476201

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Axl Polyclonal Antibody, 100ul[BT-AP00783] Dry Bath Additionally| this gene supports metastaticThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3 Axl Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin like motifs at the N terminal, followed by two fibronectin type III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K dependent protein growth arrest specific 6 (Gas6).

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Description

Additionally| this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer

and has glycosaminoglycan attachment sites in the acidic C-terminal region

Mutations in BRCA1 are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers

This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis

The protein functions to initiate or augment the early phase of T-cell activation

Axl Polyclonal Antibody, 100ul[BT-AP00783] Dry Bath Additionally| this gene supports metastaticThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3 Axl Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin like motifs at the N terminal, followed by two fibronectin type III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K dependent protein growth arrest specific 6 (Gas6).

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