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GIT1 Polyclonal Antibody, 100ul Mammalian Expression and it is located in

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GIT1 Polyclonal Antibody, 100ul Mammalian Expression and it is located inARF GTPase activating protein GIT1 is an enzyme that in humans is encoded by the GIT1 gene. GIT1 contains an ARFGAP domain, Anykrin repeats and a GRK interacting domain. The Arf GAP domain, which enables it to act as a GTPase activating protein (GAP) for the Arf family of GTPases, has been shown to be involved in phosphorylation and inhibition of the ADRB2. If synaptic localization of GIT1 is disturbed, then this is known to affect dendritic spine

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Description

and it is located in a cluster with three other family members on chromosome 7

and in the prevention of bacterial translocation in the gut

Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion

PTM:The disulfide bond may lock the enzyme in a closed conformation under oxidized conditions

but not T-lymphoma cells

GIT1 Polyclonal Antibody, 100ul Mammalian Expression and it is located inARF GTPase activating protein GIT1 is an enzyme that in humans is encoded by the GIT1 gene. GIT1 contains an ARFGAP domain, Anykrin repeats and a GRK interacting domain. The Arf GAP domain, which enables it to act as a GTPase activating protein (GAP) for the Arf family of GTPases, has been shown to be involved in phosphorylation and inhibition of the ADRB2. If synaptic localization of GIT1 is disturbed, then this is known to affect dendritic spine

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