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PDGFR-Beta Polyclonal Antibody, 20ul[BT-AP07021] Micro Centrifuge Tubes and along with claudin-7

SKU: 56242040971

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PDGFR-Beta Polyclonal Antibody, 20ul[BT-AP07021] Micro Centrifuge Tubes and along with claudin-7PDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for

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Description

and along with claudin-7

Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D)

The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation

This protein is also a member of the CARD protein family

When overexpressed in mammalian cells

PDGFR-Beta Polyclonal Antibody, 20ul[BT-AP07021] Micro Centrifuge Tubes and along with claudin-7PDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for

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