RPB3 Polyclonal Antibody, 50ul Molecular Sciences This gene encodes a major

This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells

Mutations in this gene are associated with type 1 elliptocytosis (EL1)

The encoded protein can protect the heat-shocked cell against the harmful effects of aggregated proteins

This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain| which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor

inhibition of renin and aldosterone secretion

RPB3 Polyclonal Antibody, 50ul Molecular Sciences This gene encodes a majorThis gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21.