WBS22 Rabbit Polyclonal Antibody, 20ul RNA Synthesis This receptor is activated by

This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain| which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor

PPP1R1B encodes a bifunctional signal transduction molecule

Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene

The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily

Alternate transcriptional splice variants| encoding different isoforms| have been characterized

WBS22 Rabbit Polyclonal Antibody, 20ul RNA Synthesis This receptor is activated byThis gene encodes a protein containing a nuclear localization signal and an S adenosyl L methionine binding motif typical of methyltransferases suggesting that the encoded protein may act on DNA methylation. This gene is deleted in Williams syndrome a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11. 23. Alternatively spliced transcript variants have been found.