EF-1Beta Polyclonal Antibody, 50ul Pipette Filler Mutations in ANKRD26 are associated

Mutations in ANKRD26 are associated with autosomal dominant thrombocytopenia-2

It is proposed to regulate exchange of folded proteins for transport to the Golgi and exchange of misfolded glycoproteins for transport to the ubiquitin-proteasome pathway

The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes

Growth factor receptor-bound protein 10 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules

Also| it is thought that the presenilins are involved in the cleavage of the Notch receptor such that| they either directly regulate gamma-secretase activity| or themselves act are protease enzymes

EF-1Beta Polyclonal Antibody, 50ul Pipette Filler Mutations in ANKRD26 are associatedEEF1B2 encodes a translation elongation factor. Elongation factor 1 beta is a guanine nucleotide exchange factor involved in the transfer of aminoacylated tRNAs to the ribosome. Alternative splicing results in three transcript variants which differ only in the 5' UTR.