Crk II Monoclonal Antibody, 100ul[BT-MCA0386] Custom RNA Oligos Pseudogenes associated with this gene

Pseudogenes associated with this gene have been identified and are located on chromosome 15

While JunB sometimes antagonizes c-Jun transcriptional activity

Modulates transcription of major myofibrillar proteins

Various mutations of PMP22 are causes of Charcot-Marie-Tooth disease Type IA

The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts

Crk II Monoclonal Antibody, 100ul[BT-MCA0386] Custom RNA Oligos Pseudogenes associated with this geneThis gene encodes a member of an adapter protein family that binds to several tyrosine phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2 phosphotyrosine interaction. The N terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C