Rabbit Apolipoprotein B, APO-B ELISA Kit, 96T Human Genome Knockout Libraries The protein encoded by CHAF1B

The protein encoded by CHAF1B (chromatin assembly factor 1 subunit B) corresponds to the p60 subunit and is required for chromatin assembly after replication

Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed: 16286016)

These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system

Alternative splicing results in multiple transcript variants| some of which encode distinct isoforms| including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B)

May play a role in endometrial bleeding

Rabbit Apolipoprotein B, APO-B ELISA Kit, 96T Human Genome Knockout Libraries The protein encoded by CHAF1B