Nibrin Polyclonal Antibody, 100ul[BT-AP06020] Protein Research CCNF encodes a member of

CCNF encodes a member of the cyclin family

Mutations in KRT10 are associated with epidermolytic hyperkeratosis

Based on sequence comparison

The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5

Alternative splicing results in multiple transcript variants of AXL

Nibrin Polyclonal Antibody, 100ul[BT-AP06020] Protein Research CCNF encodes a member ofMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.