NEDD4 Rabbit Polyclonal Antibody, 20ul Cell Senescence PVRL3 encodes a member of
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NEDD4 Rabbit Polyclonal Antibody, 20ul Cell Senescence PVRL3 encodes a member ofThis gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan rich WW domains and a C terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors endocytic machinery components and
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