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PKD2(Phospho Ser876) Polyclonal Antibody, 50ul sgRNA Library Construction The intestinal cell kinase localizes

SKU: 60001937587

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PKD2(Phospho Ser876) Polyclonal Antibody, 50ul sgRNA Library Construction The intestinal cell kinase localizesThe protein encoded by this gene belongs to the protein kinase D (PKD) family of serine threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding

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Description

The intestinal cell kinase localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation

resulting from alternative splicing and encoding different isoforms

MAP kinases also known as extracellular signal-regulated kinases (ERKs)

Very low expression in other tissues such as heart

UNC45A plays a role in cell proliferation and myoblast fusion| binds progesterone receptor (PGR

PKD2(Phospho Ser876) Polyclonal Antibody, 50ul sgRNA Library Construction The intestinal cell kinase localizesThe protein encoded by this gene belongs to the protein kinase D (PKD) family of serine threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding

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