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PML Polyclonal Antibody, 100ul Cytokines Nuclear phosphoprotein which forms a

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PML Polyclonal Antibody, 100ul Cytokines Nuclear phosphoprotein which forms aPromyelocytic leukemia encoded by PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell cycle related and it regulates the p53 response to oncogenic signals. PML is often involved in the

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Description

Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor

The neuropeptides have been shown to enhance cortisol secretion from adrenal cells through the adenylate cyclase/protein kinase A signaling cascade

F-box proteins are divided into three classes depending on the interaction substrate domain each contains in addition to the F-box motif: FBXW proteins contain WD-40 domains| FBXL proteins contain leucine-rich repeats| and FBXO proteins contain either different protein-protein interaction modules or no recognizable motifs

which mediates aldosterone actions on salt and water balance within restricted target cells

and may provide diagnostic-prognostic value as a molecular marker

PML Polyclonal Antibody, 100ul Cytokines Nuclear phosphoprotein which forms aPromyelocytic leukemia encoded by PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell cycle related and it regulates the p53 response to oncogenic signals. PML is often involved in the

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