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Mcl-1(Phospho-Ser159/Thr163) Rabbit Polyclonal Antibody, 100ul Plasmid Preparation Mutations in this gene have

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PLN123.75 PLN144.75

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Mcl-1(Phospho-Ser159/Thr163) Rabbit Polyclonal Antibody, 100ul Plasmid Preparation Mutations in this gene haveThis gene encodes an anti apoptotic protein which is a member of the Bcl 2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death inducing.

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Description

Mutations in this gene have been associated with bone marrow failure syndrome 2

axon growth and formation of neuronal growth cones (By similarity)

Regulator of G protein signaling 10 protein is localized in the nucleus

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Several upstream open reading frames (uORFs) have been identified| which repress the translation of the dORF| and two of which can encode small mitochondrial membrane proteins

Mcl-1(Phospho-Ser159/Thr163) Rabbit Polyclonal Antibody, 100ul Plasmid Preparation Mutations in this gene haveThis gene encodes an anti apoptotic protein which is a member of the Bcl 2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death inducing.

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