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Plakophilin 2 Polyclonal Antibody, 100ul Serological Pipets in tumor masses and invasive

SKU: 61840707212

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Plakophilin 2 Polyclonal Antibody, 100ul Serological Pipets in tumor masses and invasivePKP2 encodes a member of the arm repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. PKP2 product may regulate the signaling activity of beta catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high

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Description

in tumor masses and invasive epithelium

and they are implicated in synaptogenesis and the modulation of neurotransmitter release

the full length nature of some of these variants has not been determined

Consequently

The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis

Plakophilin 2 Polyclonal Antibody, 100ul Serological Pipets in tumor masses and invasivePKP2 encodes a member of the arm repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. PKP2 product may regulate the signaling activity of beta catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high

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