NBPF5 Polyclonal Antibody, 50ul Capsule Filter This gene is a member

This gene is a member of the EPO/TPO family and encodes a secreted| glycosylated cytokine composed of four alpha helical bundles

Knockout studies in mice exhibit neural tube defects and defective cilia| and mutations in this gene are associated with neural tube defects in humans

Binding generally results in the modulation of the activity of the binding partner

Alternative transcript variants encoding distinct isoforms have been described

Down-regulation of this gene has been associated with a variety of human epithelial malignancies

NBPF5 Polyclonal Antibody, 50ul Capsule Filter This gene is a memberNBPF5 (neuroblastoma breakpoint family member 5) is a 351 amino acid cytoplasmic protein that is expressed in medulla and brain and belongs to the NBPF family. NBPF5 contains one NBPF domain and is encoded by a gene that maps to human chromosome 1p13. Chromosome 1 spans 260 million base pairs, contains over 3000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease associated genes, including those that are