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p21 (Acetyl Lys154) Rabbit Polyclonal Antibody, 50ul Isothermal Amplification and likely other mammals as

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p21 (Acetyl Lys154) Rabbit Polyclonal Antibody, 50ul Isothermal Amplification and likely other mammals asMay be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin dependent kinase activity preventing phosphorylation of critical cyclin dependent kinase substrates and blocking cell cycle progression. induction: By p53 mezerein (antileukemic compound) and interferon beta. PTM: Phosphorylation of Thr 145 by Akt or of Ser 146 by PKC impairs binding to

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Description

and likely other mammals as well

It binds beta-catenin and negatively regulates Wnt signaling pathway

The gene is part of a cluster of MMP genes on chromosome 11

EIF2B is involved in protein synthesis and exchanges GDP and GTP for its activation and deactivation

Among its related pathways are Platinum Pathway

p21 (Acetyl Lys154) Rabbit Polyclonal Antibody, 50ul Isothermal Amplification and likely other mammals asMay be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin dependent kinase activity preventing phosphorylation of critical cyclin dependent kinase substrates and blocking cell cycle progression. induction: By p53 mezerein (antileukemic compound) and interferon beta. PTM: Phosphorylation of Thr 145 by Akt or of Ser 146 by PKC impairs binding to

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